Purpose: To assess the effect of Self-Management Education on awareness, self-care ability and symptom burden among patients with Systemic Lupus Erythematosus at tertiary care hospital.Research design: The present study adopted a quantitative experimental one group pretest and posttest designMethods: Using non-propability purposive sampling technique, a total of 55 patients diagnosed with SLE who met the inclusion criteria were recruited. The participants received the intervention Self-management Education which comprised of pre-audio recorded power point teaching using a laptop on various aspects of SLE like meaning, risk factors, signs and symptoms diagnostic investigations, treatment, complications and self-care measures. The investigator demonstrated Self-management Education every day for a group of 4 to 5 patients for about 30 to 40 minutes followed by issue of a booklet on self management guidelines in the Rheumatology OPD. The pre and posttest included Awareness (SLE awareness questionnaire), self-care ability (Exercise of Self-care Agency Scale), symptom burden (Part-I : SLE Disease Activity Index-2000 and Part-II : SLE symptom checklist). The data were analyse through using a inferential and descriptive statisticsMajor findings: There was a significant difference in level of awareness between pre-test and post-test on 15th day at p value 0.04 and between pre-test and post-test on 30th day at p value 0.01, mean scores (18.67) of self-care ability between pre-test and post-test on 15th day, at p
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